Professional China Methotrexate Disodium Salt - High Purity USP BP EP 59-05-2 Methotrexate for Tumour Treatment – Yibai
Professional China Methotrexate Disodium Salt - High Purity USP BP EP 59-05-2 Methotrexate for Tumour Treatment – Yibai Detail:
Product name | Methotrexate |
Synonyms | (+)-Amethopterin; (+)-4-Amino-10-methylfolic acid; N-(p-(((2,4-Diamino-6-pteridinyl)methyl)methylamino)benzoyl)-L-glutamic acid |
CAS No. | 59-05-2 |
Appearance | Yellow crystalline powder |
Molecular Formula | C20H22N8O5 |
Molecular Weight | 454.44 |
Application | Medicine grade or research purpose |
Packing | As per your request |
Storage | Preserve in tight,light-resistant containers in a cool place |
Certificate of Analysis Test according to: EP9.0 Methotrexate CAS No.: 59-05-2 |
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ITEMS |
STANDARDS |
RESULTS |
Appearance | Yellow or orange, crystalline, hygroscopic powder | Complies |
Identification | IR;UV | Complies |
Solubility | Practically insoluble in water, in ethanol(96%) and in methylene chloride. It dissolves in dilute mineral acids and in dilute solutions of alkali hydroxides and carbonates. | Complies |
Water | ≤13% | 11.8% |
Related Substances | Impurity B≤0.3%Impurity C≤0.5%Impurity E≤0.3%Impurity H≤0.2%Impurity I≤0.2%Unspecified Impurities≤0.05%
Sum of impurities other than B,C&E≤0.5% |
0.04%0.45%0.03%NDND0.02%
0.04% |
Enantiomeric Purity | ≤3.0% | 1.6% |
Heavy Metals | ≤20ppm | Complies |
Sulphated Ash | ≤0.1% | 0.07% |
Residual Solvents | Ethyl ether≤500ppmAcetone≤1000ppmEthanol≤ 2000ppm | 20ppm63ppm48ppm |
Assay | 97.0~102.0% | 99.49% |
Certificate of Analysis Test according to: USP32 Methotrexate CAS No.: 59-05-2 |
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ITEMS |
STANDARDS |
RESULTS |
CHARACTERISTICS | Yellow crystalline powder | Complies |
IDENTIFICATION | IR. UV Conform | Complies |
WATER | ≤12% | 10.8% |
RESIDUE ON IGNITION | ≤0.1% | 0.07% |
Chromatographic purity | Single impurity:≤0.5% | 0.27% |
Total Impurities:≤2.0 % | 0.73% | |
SPECIFIC ROTATION | Between +19°to +24° | +21.25° |
ASSAY | 98.0~102.0% | 99.27% |
Company Information
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