Manufactur standard Paclitaxel Powder - High Purity Pharmaceutical Grade 1421373-66-1 Mesylate-AZD9291 for Cancer Treatment – Yibai

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Manufactur standard Paclitaxel Powder - High Purity Pharmaceutical Grade 1421373-66-1 Mesylate-AZD9291 for Cancer Treatment – Yibai Detail:

Product name	AZD-9291 mesylate
Synonyms	N-[2-[[2-(Dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-2-propenamide methanesulfonate (1:1)
CAS No.	1421373-66-1
Appearance	White to light yellow solid powder
Molecular Formula	C₂₈H₃₃N₇O₂.CH₄O₃S
Molecular Weight	595.71
Usage	Pharmaceutical Grade or Research purpose
Packing	As per your request
Storage	Preserve in tight,light-resistant containers in a cool place

AZD-9291 mesylate CAS:1421373-66-1
Items	Standards	Results
Appearance	White to light yellow solid powder	Light yellow solid powder
Identification	By IR	Complies
Identification	By HPLC	Complies
Solubility	Soluble in Dimethylsulfoxide,slightly soluble in Ethanol and Acetonitrile,with pH dependent aqueous solubility	Complies
Water Content(KF)	≤ 1.00%	0.42%
Residue on Ignition	≤ 0.10%	0.05%
Heavy Metal	≤ 20ppm	Complies
Mesylate	15.20%~18.20%	15.90%
Residual Solvents	Acetonitrile: ≤410ppm	ND
	Acetone: ≤5000ppm	ND
	Tetrahydrofuran: ≤720ppm	ND
Related Substances	Maximum single impurity: ≤0.20%	0.17%
Related Substances	Total impurities: ≤1.00%	0.25%
Particle Size	D90: ≤100μm	57.97%
Assay (HPLC basis on drying)	98.00%~102.00%	99.80%
Reference Standard	In-house Standard

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