High reputation Melatonine Powder - High Purity 540737-29-9 Tofacitinib citrate for JAK Pathway Inhibitor – Yibai

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High reputation Melatonine Powder - High Purity 540737-29-9 Tofacitinib citrate for JAK Pathway Inhibitor – Yibai Detail:

Product name	Tofacitinib Citrate
Synonyms	(3R,4R)-1-(Cyanoacetyl)-4-methyl-N-methyl-N-1H-pyrrolo[2,3-d]pyrimidin-4-yl-3-piperidinamine 2-hydroxy-1,2,3-propanetricarboxylate; CP 690500-10; CP 690550-10; (3R,4R)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-beta-oxo-1-piperidinepropanenitrile 2-Hydroxy-1,2,3-propanetricarboxylate
CAS No.	540737-29-9
Appearance	Off white to white powder
Molecular Formula	C₁₆H₂₀N₆O.C₆H₈O₇
Molecular Weight	504.50
Application	Pharmaceutical grade or research purpose
Packing	As per your request
Storage	Preserve in tight,light-resistant containers in a cool place

Tofacitinib Citrate (CAS #540737-29-9)
ITEMS	STANDARDS	RESULTS
Appearance	Off white to white powder	Off white powder
Identification	HPLC; IR; HNMR	Complies
Solubility	Soluble in DMSO at 100mg/ml, very poorly soluble in ethanol, sparingly soluble in water etc.	Complies
Loss on Drying	≤0.5%	0.12%
Residue on ignition	≤0.1%	0.05%
Heavy metals	≤10ppm	Complies
Related Substances	Diastereomer (RS+SR) ≤0.1% Single Impurity ≤0.15% Total impurities ≤1.0%	0.05% 0.14% 0.18%
Enantiomorphism Isomers	≤0.2%	Complies
Residual Solvents	Ethanol ≤5000ppm Methanol ≤3000ppm Toluene ≤890ppm	Complies
Citrate Content	36.2%~40%	37.8%
Purity	≥99.0%	99.38%
Assay	60.68%~63.16% of Tofacitinib INN 98%~102% of Tofacitinib Citrate INN	62.04% 99.12%
Conclusion：Complies

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√ Two signed long term GMP workshops;
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